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Review
. 2023 Apr;392(1):7-20.
doi: 10.1007/s00441-022-03644-7. Epub 2022 Jun 4.

Non-human primates in prion diseases

Emmanuel E Comoy  1 , Jacqueline Mikol  2 , Jean-Philippe Deslys  2
Affiliations
Review

Non-human primates in prion diseases

Emmanuel E Comoy et al. Cell Tissue Res. 2023 Apr.

Abstract

The fascinating history of prion diseases is intimately linked to the use of nonhuman primates as experimental models, which brought so fundamental and founding information about transmissibility, pathogenesis, and resistance of prions. These models are still of crucial need for risk assessment of human health and may contribute to pave a new way towards the moving field of prion-like entities which now includes the main human neurodegenerative diseases (especially Alzheimer's and Parkinson's diseases).

Keywords: Alzheimer’s disease; Creutzfeldt-Jakob disease; Nonhuman primate; Prion; Prion-like diseases; Transmission.

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