2022 Update on Clinical Management of Graves Disease and Thyroid Eye Disease

Thanh D Hoang¹, Derek J Stocker², Eva L Chou³, Henry B Burch⁴

Affiliations

¹ Division of Diabetes, Endocrinology and Metabolism, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
² Department of Radiology, Nuclear Medicine Service, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Departments of Internal Medicine, Pathology, and Radiologic Sciences Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
³ Department of Ophthalmology, Oculoplastic Service, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
⁴ Division of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 6707 Democracy Boulevard, Room 6054, Bethesda, MD 20892-5460, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. Electronic address: Henry.Burch@nih.gov.

PMID: 35662442
PMCID: PMC9174594
DOI: 10.1016/j.ecl.2021.12.004

Review

2022 Update on Clinical Management of Graves Disease and Thyroid Eye Disease

Thanh D Hoang et al. Endocrinol Metab Clin North Am. 2022 Jun.

. 2022 Jun;51(2):287-304.

doi: 10.1016/j.ecl.2021.12.004. Epub 2022 May 11.

Authors

Thanh D Hoang¹, Derek J Stocker², Eva L Chou³, Henry B Burch⁴

Affiliations

¹ Division of Diabetes, Endocrinology and Metabolism, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
² Department of Radiology, Nuclear Medicine Service, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Departments of Internal Medicine, Pathology, and Radiologic Sciences Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
³ Department of Ophthalmology, Oculoplastic Service, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
⁴ Division of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 6707 Democracy Boulevard, Room 6054, Bethesda, MD 20892-5460, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. Electronic address: Henry.Burch@nih.gov.

PMID: 35662442
PMCID: PMC9174594
DOI: 10.1016/j.ecl.2021.12.004

Abstract

The management of hyperthyroidism and extrathyroidal manifestations of Graves disease remains complex. Considerations that include patient preference, age, comorbidity, pregnancy, tobacco smoking, and social determinants of health must all be weaved into a cohesive management plan. A multidisciplinary team is required to manage all aspects of Graves disease, particularly thyroid eye disease, for which new therapeutic options are now available.

Keywords: Antithyroid drugs; Graves disease; Hyperthyroidism; Radioiodine therapy; Thyroid eye disease; Thyroidectomy.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

References

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2022 Update on Clinical Management of Graves Disease and Thyroid Eye Disease

Affiliations

2022 Update on Clinical Management of Graves Disease and Thyroid Eye Disease

Authors

Affiliations

Abstract

Conflict of interest statement

References

Publication types

MeSH terms

Substances

Grants and funding

LinkOut - more resources

Full Text Sources

Medical