Editorial: Exploring Maternal-Fetal Pharmacology Through PBPK Modeling Approaches
- PMID: 35664868
- PMCID: PMC9159273
- DOI: 10.3389/fped.2022.880402
Editorial: Exploring Maternal-Fetal Pharmacology Through PBPK Modeling Approaches
Keywords: PBPK; maternal-fetal; modeling and simulation; pharmacokinetics; physiologically – based pharmacokinetic model; pregnancy.
Conflict of interest statement
AD is an employee of Bayer AG and uses Open Systems Pharmacology software, tools, and models in his professional role. The remaining author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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- Editorial on the Research Topic Exploring Maternal-Fetal Pharmacology Through PBPK Modeling Approaches
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References
-
- Van Calsteren K, Gersak K, Sundseth H, Klingmann I, Dewulf L, Van Assche A, et al. . Position statement from the European Board and College of Obstetrics & Gynaecology (EBCOG): the use of medicines during pregnancy–call for action. Eur J Obstetr Gynecol Reprod Biol. (2016) 201:189–91. 10.1016/j.ejogrb.2016.04.004 - DOI - PubMed
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