Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Sep;51(7):102419.
doi: 10.1016/j.jogoh.2022.102419. Epub 2022 Jun 3.

Local injection of methotrexate ultrasound guided-transvaginal

Affiliations
Free article

Local injection of methotrexate ultrasound guided-transvaginal

Marie Allegrini et al. J Gynecol Obstet Hum Reprod. 2022 Sep.
Free article

Abstract

Non-tubal ectopic pregnancies can be located in the uterine portion of the tube (interstitial or cornual), in the cervix (cervical), in a cesarian scar, in the ovary, or intra-abdominally. Even though they are rare, they are associated with a high mortality. Invasive surgeries such as cornuectomy and hysterectomy were common to treat them in case of hemorrhage. Thanks to recent advances in imaging techniques, diagnosis of non-tubal ectopic pregnancy is made earlier and conservative management has been developed in order to respect fertility of patients. Beyond these treatments, systemic or local injection of Methotrexate shows very good success. In the article, we aimed to describe the technics of vaginal injection of in situ methotrexate with ultrasound guidance.

Keywords: Fertility; Methotrexate in situ injection-ultrasound; Non-tubal ectopic pregnancy; Surgery; Vaginal.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest Authors declare no conflict of interest.

Substances