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Clinical Trial
. 1986 Dec;22(6):725-8.
doi: 10.1111/j.1365-2125.1986.tb02965.x.

The effects of age on carbamazepine pharmacokinetics and adverse effects

N Hockings, A Pall, J Moody, A V Davidson, D L Davidson
Clinical Trial

The effects of age on carbamazepine pharmacokinetics and adverse effects

N Hockings et al. Br J Clin Pharmacol. 1986 Dec.

Abstract

The pharmacokinetics and effect of single oral doses of carbamazepine (400 mg) were compared in a group of six young volunteers aged between 20 and 25 years, and a second group of five elderly volunteers aged between 66 and 84 years. No age related changes in salivary or plasma pharmacokinetics or in psychomotor function were detected.

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