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Observational Study
. 2022 Jul;66(4):350-357.
doi: 10.1007/s10384-022-00924-1. Epub 2022 Jun 7.

Clinical performance of a custom-designed soft contact lens in patients with keratoconus and intolerance to rigid contact lenses

Takahiro Hiraoka  1 , Gaku Kiuchi  2 , Reia Hiraoka  2 , Tetsuro Oshika  2
Affiliations
Observational Study

Clinical performance of a custom-designed soft contact lens in patients with keratoconus and intolerance to rigid contact lenses

Takahiro Hiraoka et al. Jpn J Ophthalmol. 2022 Jul.

Abstract

Purpose: This study evaluated the efficacy and safety of YOUSOFT® soft contact lens (CL) (TOMEY-CL) in patients with keratoconus and intolerance to rigid CLs.

Study design: Retrospective observational study.

Methods: Thirty-six eyes of 20 patients (14 men and 6 women) with keratoconus and rigid CL intolerance were included in the study. Four patients were unilateral. The mean age was 33.1 ± 11.7 (± standard deviation) years, the mean spherical refractive error was - 4.99 ± 3.97 D, and the mean cylindrical refractive error was - 3.39 ± 2.13 D. The following examinations were performed at baseline and were repeated at every visit; refractometry, visual acuity, corneal topography and pachymetry with an anterior OCT system. Corneal endothelial cell density was evaluated at baseline and every 6 months. Slit-lamp examination was also performed to confirm the CL condition and ocular health at every visit.

Results: Seventeen patients (85%) were able to continue using the Yousoft. Among 3 patients (15%) who dropped out, 2 were dissatisfied with their visual outcomes and one had trouble with lens handling. Uncorrected visual acuity was 1.08 ± 0.43 (range: 0.22 to 2.00) logMAR at baseline, and best CL-corrected visual acuity was 0.01 ± 0.15 (range: - 0.18 to 0.40) logMAR, showing a significant improvement after wearing Yousoft (P < 0.0001). The endothelial cell density did not change significantly, with 2373 ± 482 at baseline and 2402 ± 464 cells/mm2 at the latest visit after lens prescription (P = 0.351). There were no severe complications such as corneal infiltrates or infectious keratitis throughout the study period.

Conclusions: This study showed the efficacy and acceptable safety of Yousoft for patients with keratoconus and intolerance to rigid CLs.

Keywords: Comfort; Intolerance to rigid contact lens; Keratoconus; Satisfaction; Yousoft.

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References

    1. Krachmer JH, Feder RS, Belin MW. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol. 1984;28:293–322. - DOI
    1. Jinabhai A, Radhakrishnan H, Tromans C, O’Donnell C. Visual performance and optical quality with soft lenses in keratoconus patients. Ophthalmic Physiol Opt. 2012;32:100–16. - DOI
    1. Kennedy RH, Bourne WM, Dyer JA. A 48-year clinical and epidemiologic study of keratoconus. Am J Ophthalmol. 1986;101:267–73. - DOI
    1. Romero-Jimenez M, Santodomingo-Rubido J, Wolffsohn JS. Keratoconus: a review. Cont Lens Anterior Eye. 2010;33:157–66. - DOI
    1. Georgiou T, Funnell C, Cassels-Brown A, O’Conor R. Influence of ethnic origin on the incidence of keratoconus and associated atopic disease in Asians and white patients. Eye. 2004;18:379. - DOI

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