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Observational Study
. 2022 Sep;37(9):2673-2681.
doi: 10.1111/jocs.16663. Epub 2022 Jun 7.

Outcome of submitral aneurysm

Puneet Aggarwal  1 , Abhinav Shrivastava  1 , Dheerendra Kuber  1 , Ranjit Kumar Nath  1 , Santosh Kumar Sinha  2 , Tarun Kumar  1 , Ajay Raj  1 , Bhagya Narayan Pandit  1
Affiliations
Observational Study

Outcome of submitral aneurysm

Puneet Aggarwal et al. J Card Surg. 2022 Sep.

Abstract

Introduction: Submitral aneurysm is a rare cardiac entity with outpouching in relation to the posterior annulus of the mitral valve. Multiple etiology have been described with the role of infection and inflammation with varied clinical presentation in different case reports. However, the literature on clinical outcome and follow-up is lacking.

Material and method: This retrospective, observational study included all the adult patients (>18 years) who were diagnosed with a submitral aneurysm. Epidemiological, demographic, laboratory, clinical management, and outcome data were extracted and followed for the endpoints of cardiac death, noncardiac death, recurrent hospitalization (due to heart failure, rupture, arrhythmic events, embolic events), surgical repair, and echocardiography parameters for mitral regurgitation or change in the size of the left ventricle for 1-year postdischarge from the index hospitalization.

Results: A total of 10 patients were enrolled in the study with a mean age of 31.2 ± 11.1 years. Possible etiology could be established in only five (50%) patients (two patients had tuberculosis and three patients had acute coronary syndrome). At index hospitalization, nine (90%) patients had heart failure, two (20%) patients had rupture of a submitral aneurysm, four patients underwent surgery, and one patient expired. On follow-up of 1 year, one more patient underwent surgical repair while three patients expired.

Conclusion: A submitral aneurysm is a rare cardiac entity with poor outcomes. Surgical repair with or without mitral valve replacement plays a definitive role in management.

Keywords: acute coronary syndrome; congestive heart failure; submitral aneurysm; tuberculosis.

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References

REFERENCES

    1. Awasthy N, Shrivastava S. Submitral aneurysm: an antenatal diagnosis. Ann Pediatr Cardiol. 2013;6(2):164-166. doi:10.4103/0974-2069.115270
    1. LURIE AO. Left ventricular aneurysm in the African. Br Heart J. 1960;22(2):181-188. doi:10.1136/hrt.22.2.181
    1. Ribeiro PJ, Mendes RG, Vicente WV, Menardi AC, Evora PR. Submitral left ventricular aneurysm. Case report and review of published Brazilian cases. Arq Bras Cardiol. 2001;76(5):395-402. doi:10.1590/s0066-782x2001000500006
    1. Prasad K, Gupta H, Sihag BK, et al. Submitral aneurysm of varied aetiologies: a case series. Eur Heart J Case Rep. 2021;5(2):ytab066. doi:10.1093/ehjcr/ytab066
    1. Shirota K, Yano Y, Hayase S, et al. A case of submitral left ventricular pseudoaneurysm following mitral valve replacement for infective endocarditis. Kyobu Geka. 1998;51(5):410-414.

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