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Review
. 2023 Feb;16(1):87-96.
doi: 10.1007/s12265-022-10284-3. Epub 2022 Jun 7.

Exosomes in Myocardial Infarction: Therapeutic Potential and Clinical Application

Wenjian Nian  1 , Cong Fu  2   3
Affiliations
Review

Exosomes in Myocardial Infarction: Therapeutic Potential and Clinical Application

Wenjian Nian et al. J Cardiovasc Transl Res. 2023 Feb.

Abstract

Myocardial infarction (MI) remains the leading fatal disease in the world, and with subsequent adverse ventricular remodeling often leading to the development of heart failure, finding new ways to improve the prognosis of MI is important. Exosomes are extracellular vesicles of 30-150 nm secreted by various cells in the body. It is now well recognized that exosomes play an important role in MI, and exosomes may become a new approach to post-MI treatment. It is valuable to study how exosomes are involved in post-MI progression and how exosomes can be modified to improve their effectiveness. In this review, we focus on summarizing the therapeutic potential of exosomes for MI and the current status of clinical applications to provide evidence for the formal use of exosomes in the clinic.

Keywords: Clinical application; Exosome; Myocardial infarction; Therapeutic potential.

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