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. 2022 Jul 1;64(7):557-561.
doi: 10.1097/JOM.0000000000002545. Epub 2022 Jun 8.

Progressive Massive Fibrosis Risk Factors: A Retrospective Cross-Sectional Study

Gülden Sari  1 , Adem Koyuncu, Cebrail Şimşek
Affiliations

Progressive Massive Fibrosis Risk Factors: A Retrospective Cross-Sectional Study

Gülden Sari et al. J Occup Environ Med. .

Abstract

Objective: This study aimed to determine the occupational and clinical characteristics of patients with progressive massive fibrosis (PMF) and factors related to the development and severity of PMF.

Methods: Personal, occupational, radiological, and functional findings of 129 patients diagnosed with PMF were evaluated.

Results: Sandblasting workers were found to be diagnosed with pneumoconiosis at an earlier age than those in other professions. The dust exposure durations of sandblasting and ceramic workers were significantly less than those of workers in other occupations. Statistically, a significant negative correlation was found between lung functions and small opacity size, small opacity profusion score, and large opacity size. No relationship was found between large opacity size and smoking status, concomitant tuberculosis, and duration of dust exposure.

Conclusions: An effective surveillance system that considers factors that accelerate pneumoconiosis progression should be established.

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Conflict of interest statement

Conflict of interest: No conflict of interest was declared by the authors.

References

    1. Jardin C, Wallaert B. Chapter 51—silicosis and coal worker's pneumoconiosis. In: Spiro SG, Silvestri GA, Agustí A, eds. Clinical Respiratory Medicine . 4th ed. Philadelphia, PA: W.B. Saunders; 2012:637–644.
    1. Adverse effects of crystalline silica exposure. American Thoracic Society Committee of the Scientific Assembly on Environmental and Occupational Health. Am J Respir Crit Care Med . 1997;155:761–768.
    1. Blackley DJ, Halldin CN, Laney AS. Resurgence of a debilitating and entirely preventable respiratory disease among working coal miners. Am J Respir Crit Care Med . 2014;190:708–709.
    1. Ferreira AS, Moreira VB, Ricardo HM, Coutinho R, Gabetto JM, Marchiori E. Progressive massive fibrosis in silica-exposed workers. High-resolution computed tomography findings. J Bras Pneumol . 2006;32:523–528.
    1. Friedman GK, Harrison R, Bojes H, Worthington K, Filios M. Notes from the field: silicosis in a countertop fabricator—Texas, 2014. MMWR Morb Mortal Wkly Rep . 2015;64:129–130.