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Review
. 2021 Aug 24;21(1):853-861.
doi: 10.1007/s40200-021-00880-6. eCollection 2022 Jun.

Genomic medicine on the frontier of precision medicine

Mandana Hasanzad  1   2 , Negar Sarhangi  2 , Anoosh Naghavi  3 , Ehsan Ghavimehr  1 , Fatemeh Khatami  4 , Sima Ehsani Chimeh  5 , Bagher Larijani  6 , Hamid Reza Aghaei Meybodi  2
Affiliations
Review

Genomic medicine on the frontier of precision medicine

Mandana Hasanzad et al. J Diabetes Metab Disord. .

Abstract

Genomic medicine has created a great deal of hope since the completion of the Human Genome Project (HGP). Genomic medicine promises disease prevention and early diagnosis in the context of precision medicine. Precision medicine as a scientific discipline has introduced as an evolution in medicine. The rapid growth of high-development technologies permits the assessment of biological systems. Study of the integrated profiles of omics, such as genome, transcriptome, proteome and other omics information lead to significant advances in personalized and precision medicine. In the context of precision medicine, pharmacogenomics can play an important role in order to discriminate responders and non-responders to medications and avoiding toxicity and achieving the optimum dose. So precision medicine in accordance with genomic medicine will transform medicine from conventional evidence-based medicine in the diagnosis and treatment towards precision based-medicine. In this review, we have summarized the related issues for genomic medicine and precision medicine.

Keywords: GWAS; Genomic medicine; Omics; Pharmacogenomics; Precision medicine.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

References

    1. National Cancer Institute (NIH). NCI is the nation’s leader in cancer research. Available at: https://www.cancer.gov/.
    1. Narad P, Kirthanashri S. Introduction to omics. Omics approaches, technologies and applications. Springer; 2018. pp. 1–10.
    1. Food and Drug Adminstration (FDA). Department of Health and Human Services. Table of pharmacogenomic biomarkers in drug labeling. Available at: https://www.fda.gov/drugs/scienceresearch/ucm572698.htm.
    1. Roth SC. What is genomic medicine? J Med Libr Assoc. 2019;107(3):442–8. - PMC - PubMed
    1. Davies K. The era of genomic medicine. Clin Med (Lond) 2013;13(6):594–601. doi: 10.7861/clinmedicine.13-6-594. - DOI - PMC - PubMed

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