Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb 10;21(1):475-481.
doi: 10.1007/s40200-022-00998-1. eCollection 2022 Jun.

Prevalence of vitamin D deficiency and its association with metabolic syndrome among the elderly population of Birjand, Iran

Fatemeh Hoseinzadeh-Chahkandak  1 , Tayebeh Zeinali  2 , Fatemeh Salmani  3 , Mitra Moodi  4 , Farshad Sharifi  5 , Mehran Rahimlou  6 , Elham Ansarifar  1
Affiliations

Prevalence of vitamin D deficiency and its association with metabolic syndrome among the elderly population of Birjand, Iran

Fatemeh Hoseinzadeh-Chahkandak et al. J Diabetes Metab Disord. .

Abstract

Background: With increasing life expectancy and the aging population of most countries, attention to the diseases of old age has also increased. Due to the high prevalence of vitamin D deficiency in the elderly, the present study was designed and performed to investigate the relationship between serum vitamin D levels in Iranian elderly with the risk of metabolic syndrome (MetS).

Methods: This study was conducted on an elderly population of Birjand (60 and older) in the urban and rural areas of the city. In 1325 elderly men and women, with age range of 60 and older, serum 25-hydroxyvitamin D, anthropometric measurements and laboratory variables were measured.

Results: Twenty-eight percent of the elderly participants in the study had vitamin D deficiency. We found that participants with higher 25(OH)D had lower odds for elevated waist circumference (WC) (OR = 0.91, 95% CI 0.83-0.98), reduced HDL (OR = 0.96, 95% CI 0.86-0.97) and elevated fasting blood sugar (FBS) (OR = 0.96, 95% CI 0.89-0.98). We not found any significant association between 25(OH)D levels and other MetS components.

Conclusion: Higher 25(OH)D levels in the elderly are linked to a reduced prevalence of MetS and, specifically, higher levels of favorable HDL-C, WC and FBS. Further intervention studies are needed to substantiate the results of this study.

Keywords: Elderly; Elevated waist circumference; Metabolic syndrome; Vitamin D.

PubMed Disclaimer

Conflict of interest statement

Competing interestsThe authors declare that they have no competing interests.

Similar articles

See all similar articles

Cited by

References

    1. Moodi M, Firoozabadi MD, Kazemi T, Payab M, Ghaemi K, Miri MR, Sharifzadeh G, Fakhrzadeh H, Ebrahimpur M, Arzaghi SM. Birjand longitudinal aging study (BLAS): the objectives, study protocol and design (wave I: baseline data gathering) J Diabetes Metab Disord. 2020;19:551–559. doi: 10.1007/s40200-020-00504-5. - DOI - PMC - PubMed
    1. Agarwal S, Tooze JA, Bauer DC, Cauley JA, Harris TB, Koster A, Womack CR, Kritchevsky SB, Houston DK. Association between 25-hydroxyvitamin D and metabolic syndrome in older adults: the health, aging and body composition study. Int J Endocrinol. 2021;2021. - PMC - PubMed
    1. Maghbooli Z, Hossein-nezhad A, Karimi F, Shafaei AR, Larijani B. Correlation between vitamin D3 deficiency and insulin resistance in pregnancy. Diabetes Metab Res Rev. 2008;24:27–32. doi: 10.1002/dmrr.737. - DOI - PubMed
    1. Vitezova A, Zillikens M, Van Herpt T, Sijbrands E, Hofman A, Uitterlinden A, Franco O, Kiefte-de Jong J. Vitamin D status and metabolic syndrome in the elderly: the Rotterdam Study. Eur J Endocrinol. 2015;172:327–335. doi: 10.1530/EJE-14-0580. - DOI - PubMed
    1. Leite M, Nicolosi A, Firmo J, Lima-Costa M. Features of metabolic syndrome in non-diabetic Italians and Brazilians: a discriminant analysis. Int J Clin Pract. 2007;61:32–38. doi: 10.1111/j.1742-1241.2006.01139.x. - DOI - PubMed

LinkOut - more resources