The use of platelet-rich plasma in management of musculoskeletal pain: a narrative review
- PMID: 35673831
- PMCID: PMC9273137
- DOI: 10.12701/jyms.2022.00290
The use of platelet-rich plasma in management of musculoskeletal pain: a narrative review
Abstract
Musculoskeletal pain is the most common pain reported by patients. Platelet-rich plasma (PRP) is widely used to treat musculoskeletal pain. However, the efficacy of PRP to treat this pain remains controversial. This review highlights the application of PRP in the treatment of musculoskeletal pain. PRP treatment appears to reduce pain and improve function in patients with musculoskeletal pain. However, there are limitations to the currently published studies. These limitations include the PRP preparation methods, type of activators, types of pathology to be treated, methods and times of administration, and association of PRP with other treatments.
Keywords: Humans; Musculoskeletal pain; Pain management; Platelet-rich plasma.
Conflict of interest statement
No potential conflict of interest relevant to this article was reported.
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References
-
- Casser HR, Schaible HG. Musculoskeletal pain. Schmerz. 2015;29:486–8. 490–5. - PubMed
-
- Marks R. Qigong and musculoskeletal pain. Curr Rheumatol Rep. 2019;21:59. - PubMed
-
- Hawker GA. The assessment of musculoskeletal pain. Clin Exp Rheumatol. 2017;35(5 Suppl 107):8–12. - PubMed
-
- Sepúlveda F, Baerga L, Micheo W. The role of physiatry in regenerative medicine: the past, the present, and future challenges. PM R. 2015;7(4 Suppl):S76–80. - PubMed
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