Biting into a union of oncology and metabolism through leukemic stem cells
- PMID: 35675797
- DOI: 10.1016/j.cmet.2022.05.006
Biting into a union of oncology and metabolism through leukemic stem cells
Abstract
In this issue of Cell Metabolism, Liu et al. demonstrate that Prmt7 can regulate the onset and progression of leukemogenesis by inhibiting self-renewal capacity of leukemic stem cells (LSCs) as modeled in a murine version of chronic myeloid leukemia (CML).
Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML.Cell Metab. 2022 Jun 7;34(6):818-835.e7. doi: 10.1016/j.cmet.2022.04.004. Epub 2022 May 3. Cell Metab. 2022. PMID: 35508169
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