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. 2022 Oct;15(4):774-780.
doi: 10.1111/ases.13092. Epub 2022 Jun 8.

Comparative assessment of multiple-tract vs single-tract percutaneous nephrolithotomy

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Comparative assessment of multiple-tract vs single-tract percutaneous nephrolithotomy

Olga Savko et al. Asian J Endosc Surg. 2022 Oct.

Abstract

Introduction: To investigate the efficacy and safety of multi-tract percutaneous nephrolithotomy (PNL) against the benchmark of the single-tract approach.

Methods: A retrospective analysis of 391 consecutive PNL procedures was conducted in our tertiary referral center between April 2016 and March 2020. Clinical outcome parameters such as stone-free rate, operation time, postoperative complications according to Clavien-Dindo, length of hospital stay and time to ipsilateral recurrence resulting in active treatment were assessed.

Results: Multi-tract PNL and single-tract PNL were performed in 37 (9%) and 354 (91%) cases respectively. At baseline, compared to single-tract PNL, multi-tract PNL cases were characterized by significantly larger stone burden (2.62 vs 0.97 cm3 , P < .00), lower Hounsfield units (HU) (751 vs 1017 HU, P < .01), a more complex S.T.O.N.E. (size, tract length, obstruction, number of calyces, essence) score (P < .00) and a higher rate of high-risk stone formers (59 vs 19%, P < .00). Analysis of outcome revealed shorter operation time and length of hospital stay for single-tract PNL compared to multi-tract PNL (P < .01). However, the difference in terms of stone-free rates (92% vs 88%), complication rates (43% vs 28%) and time to active retreatment due to ipsilateral recurrence was not statistically significant (P > .05).

Conclusion: In this retrospective single-center analysis, a multi-tract PNL has been proved to be an efficient and safe expansion of single-tract PNL for large stone burden and complex kidney stone disease. Future prospective research should focus on the procedure's potential effectiveness in reducing the number of interventions until stone-free status in patients with massive stone disease.

Keywords: multiple-tract; percutaneous nephrolithotomy; staghorn calculi.

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References

REFERENCES

    1. Preminger GM, Assimos DG, Lingeman JE, Nakada SY, Pearle MS, Wolf JS Jr. Chapter 1: AUA guideline on management of staghorn calculi: diagnosis and treatment recommendations. J Urol. 2005;173(6):1991-2000. doi:00005392-200506000-00048 [pii]. doi:10.1097/01.ju.0000161171.67806.2a
    1. Türk C, Neisius A, Petřík A, Seitz C, Skolarikos A, Somani B, Thomas K, Gambaro G, Davis NF, Donaldson JF, Lombardo R, Tzelves L (2021) Urolithiasis EAU Guidelines. Edn. presented at the EAU Annual Congress Milan 2021.
    1. Balaji S, Ganpule A, Herrmann T, Sabnis R, Desai M. Contemporary role of multi-tract percutaneous nephrolithotomy in the treatment of complex renal calculi. Asian J Urol. 2020;7(2):102-109. doi:S2214-3882(19)30141-9 [pii]. doi:10.1016/j.ajur.2019.12.012
    1. Rassweiler JJ, Renner C, Eisenberger F. The management of complex renal stones. BJU Int. 2000;86(8):919-928. doi:bju906 [pii]. doi:10.1046/j.1464-410x.2000.00906.x
    1. Mishra S, Sabnis RB, Desai M. Staghorn morphometry: a new tool for clinical classification and prediction model for percutaneous nephrolithotomy monotherapy. J Endourol. 2012;26(1):6-14. doi:10.1089/end.2011.0145

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