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Review
. 2022 Jun 2:17:2505-2533.
doi: 10.2147/IJN.S363282. eCollection 2022.

Mycology-Nanotechnology Interface: Applications in Medicine and Cosmetology

Daljeet Singh Dhanjal #  1 , Parul Mehra #  2 , Sonali Bhardwaj #  1 , Reena Singh  1 , Parvarish Sharma  3 , Eugenie Nepovimova  4 , Chirag Chopra  1 , Kamil Kuca  4   5
Affiliations
Review

Mycology-Nanotechnology Interface: Applications in Medicine and Cosmetology

Daljeet Singh Dhanjal et al. Int J Nanomedicine. .

Abstract

In today's time, nanotechnology is being utilized to develop efficient products in the cosmetic and pharmaceutical industries. The application of nanotechnology in transforming bioactive material into nanoscale products substantially improves their biocompatibility and enhances their effectiveness, even when used in lower quantities. There is a significant global market potential for these nanoparticles because of which research teams around the world are interested in the advancements in nanotechnology. These recent advances have shown that fungi can synthesize metallic nanoparticles via extra- and intracellular mechanisms. Moreover, the chemical and physical properties of novel metallic nanoparticles synthesised by fungi are improved by regulating the surface chemistry, size, and surface morphology of the nanoparticles. Compared to chemical synthesis, the green synthesis of nanoparticles offers a safe and sustainable approach for developing nanoparticles. Biosynthesised nanoparticles can potentially enhance the bioactivities of different cellular fractions, such as plant extracts, fungal extracts, and metabolites. The nanoparticles synthesised by fungi offer a wide range of applications. Recently, the biosynthesis of nanoparticles using fungi has become popular, and various ways are being explored to maximize nanoparticles synthesis. This manuscript reviews the characteristics and applications of the nanoparticles synthesised using the different taxa of fungi. The key focus is given to the applications of these nanoparticles in medicine and cosmetology.

Keywords: biological application; biosynthesis; fungi; nanoparticles; nanotechnology.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Basic mechanism flowchart of fungal-based biosynthesis of nanoparticles.
Figure 2
Figure 2
Schematic representation of intracellular and extracellular nanoparticle formation by fungi.
Figure 3
Figure 3
Diagrammatic illustration of top-down method” and “bottom-up method.
Figure 4
Figure 4
Comparative schematic showing the bacterial and fungal mediated nanoparticle synthesis.
Figure 5
Figure 5
Schematic diagram showing the mechanism of antibacterial activity of functionalized metallic nanoparticles [Image Courtesy: 166. Under CC-BY license].
Figure 6
Figure 6
Diverse application of fungal based nanoparticles in the field of biomedicine.
See this image and copyright information in PMC

References

    1. Lowry GV, Avellan A, Gilbertson LM. Opportunities and challenges for nanotechnology in the agri-tech revolution. Nat Nanotechnol. 2019;14(6):517–522. doi:10.1038/s41565-019-0461-7 - DOI - PubMed
    1. Mittapally S, Aziz A, Student A, Afnan AA. A review on nanotechnology in cosmetics. Pharma Innov Int J. 2019;8(4):668–671.
    1. Effiong DE, Uwah TO, Jumbo EU, et al. Nanotechnology in cosmetics: basics, current trends and safety concerns—A review. Adv Nanopart. 2019;9(1):1–22. doi:10.4236/ANP.2020.91001 - DOI
    1. Erkoc P, Ulucan-Karnak F. Nanotechnology-based antimicrobial and antiviral surface coating strategies. Prosthes. 2021;3(1):25–52. doi:10.3390/PROSTHESIS3010005 - DOI
    1. Tao C. Antimicrobial activity and toxicity of gold nanoparticles: research progress, challenges and prospects. Lett Appl Microbiol. 2018;67(6):537–543. doi:10.1111/LAM.13082 - DOI - PubMed