Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun;37(3):506-512.
doi: 10.3803/EnM.2022.1429. Epub 2022 Jun 9.

Bone Mineral Density Screening Interval and Transition to Osteoporosis in Asian Women

Hyunju Park  1 , Heera Yang  1 , Jung Heo  1 , Hye Won Jang  2 , Jae Hoon Chung  1 , Tae Hyuk Kim  1 , Yong-Ki Min  1 , Sun Wook Kim  1
Affiliations

Bone Mineral Density Screening Interval and Transition to Osteoporosis in Asian Women

Hyunju Park et al. Endocrinol Metab (Seoul). 2022 Jun.

Abstract

Backgruound: Bone mineral density (BMD) testing is indicated for women aged 65 years, but screening strategies for osteoporosis are controversial. Currently, there is no study focusing on the BMD testing interval in Asian populations. The current study aimed to evaluate the estimated time interval for screening osteoporosis.

Methods: We conducted a study of 6,385 subjects aged 50 years and older who underwent dual-energy X-ray absorptiometry screening more than twice at Samsung Medical Center as participants in a routine health checkup. Subjects were divided based on baseline T-score into mild osteopenia (T-score, <-1.0 to >-1.5), moderate osteopenia (T-score, ≤-1.5 to >-2.0), and severe osteopenia (T-score, ≤-2.0 to >-2.5). Information about personal medical and social history was collected by a structured questionnaire.

Results: The adjusted estimated BMD testing interval for 10% of the subjects to develop osteoporosis was 13.2 years in mild osteopenia, 5.0 years in moderate osteopenia, and 1.5 years in severe osteopenia.

Conclusion: Our study provides extended information about BMD screening intervals in Asian female population. Baseline T-score was important for predicting BMD screening interval, and repeat BMD testing within 5 years might not be necessary in mild osteopenia subjects.

Keywords: Bone density; Bone diseases, metabolic; Osteoporosis; Screening interval.

PubMed Disclaimer

Conflict of interest statement

CONFLICTS OF INTEREST

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1.
Fig. 1.
Study population. DXA, dual-energy X-ray absorptiometry; BMD, bone mineral density; GFR, glomerular filtration rate.
Fig. 2.
Fig. 2.
Unadjusted cumulative incidence curve of osteoporosis according to baseline T-score.
See this image and copyright information in PMC

References

    1. Office of the Surgeon General (US) Rockville: Office of the Surgeon General (US); 2004. Bone health and osteoporosis: a report of the Surgeon General. - PubMed
    1. Wright NC, Looker AC, Saag KG, Curtis JR, Delzell ES, Randall S, et al. The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. J Bone Miner Res. 2014;29:2520–6. - PMC - PubMed
    1. Park EJ, Joo IW, Jang MJ, Kim YT, Oh K, Oh HJ. Prevalence of osteoporosis in the Korean population based on Korea National Health and Nutrition Examination Survey (KNHANES), 2008-2011. Yonsei Med J. 2014;55:1049–57. - PMC - PubMed
    1. US Preventive Services Task Force. Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, et al. Screening for osteoporosis to prevent fractures: US Preventive Services Task Force recommendation statement. JAMA. 2018;319:2521–31. - PubMed
    1. Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, et al. Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int. 2014;25:2359–81. - PMC - PubMed