CRISPR comes a-knock-in to reprogram antibodies in vivo

Harald Hartweger¹, Michel C Nussenzweig^{2

3}

Affiliations

¹ Laboratory for Molecular Immunology, Rockefeller University, New York, NY, USA. hhartweger@rockefeller.edu.
² Laboratory for Molecular Immunology, Rockefeller University, New York, NY, USA.
³ Howard Hughes Medical Institute, Rockefeller University, New York, NY, USA.

Comment

Harald Hartweger et al. Nat Biotechnol. 2022 Aug.

. 2022 Aug;40(8):1183-1184.

doi: 10.1038/s41587-022-01299-x.

Harald Hartweger¹, Michel C Nussenzweig^{2

3}

¹ Laboratory for Molecular Immunology, Rockefeller University, New York, NY, USA. hhartweger@rockefeller.edu.
² Laboratory for Molecular Immunology, Rockefeller University, New York, NY, USA.
³ Howard Hughes Medical Institute, Rockefeller University, New York, NY, USA.

No abstract available

Comment on

In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice.
Nahmad AD, Lazzarotto CR, Zelikson N, Kustin T, Tenuta M, Huang D, Reuveni I, Nataf D, Raviv Y, Horovitz-Fried M, Dotan I, Carmi Y, Rosin-Arbesfeld R, Nemazee D, Voss JE, Stern A, Tsai SQ, Barzel A. Nahmad AD, et al. Nat Biotechnol. 2022 Aug;40(8):1241-1249. doi: 10.1038/s41587-022-01328-9. Epub 2022 Jun 9. Nat Biotechnol. 2022. PMID: 35681059 Free PMC article.

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