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Meta-Analysis
. 2022 Oct;101(10):1174-1175.
doi: 10.1111/aogs.14403. Epub 2022 Jun 9.

Multivitamin use may lower risk of preeclampsia: A meta-analysis

Andre C Q Lo  1 , Charmaine Chu Wen Lo  2   3   4
Affiliations
Meta-Analysis

Multivitamin use may lower risk of preeclampsia: A meta-analysis

Andre C Q Lo et al. Acta Obstet Gynecol Scand. 2022 Oct.
No abstract available

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Figures

FIGURE 1
FIGURE 1
Meta‐analysis of interventional data examining the effect of multivitamin use on risk of preeclampsia irrespective of baseline preeclampsia risk (left), examining only women with increased risk of preeclampsia (middle), and excluding studies with supplementation from fortified foods (right), with stratification for risk of preeclampsia.
FIGURE 2
FIGURE 2
Meta‐analysis of adjusted observational data examining the effect of multivitamin use on risk of preeclampsia for all women (left), for women with BMI ≥25 (middle), and for women with BMI <25 (right), with stratification for timing of multivitamin use.
See this image and copyright information in PMC

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References

    1. Christiansen CH, Høgh S, Rode L, Schroll JB, Hegaard HK, Wolf HT. Multivitamin use and risk of preeclampsia: a systematic review and meta‐analysis. Acta Obstet Gynecol Scand 2022. doi:10.1111/aogs.14356. Epub ahead of print. - DOI - PMC - PubMed
    1. Vadillo‐Ortega F, Perichart‐Perera O, Espino S, et al. Effect of supplementation during pregnancy with L‐arginine and antioxidant vitamins in medical food on pre‐eclampsia in high risk population: randomised controlled trial. BMJ. 2011;342:d2901. - PMC - PubMed
    1. Wibowo N, Purwosunu Y, Sekizawa A, Farina A, Idriansyah L, Fitriana I. Antioxidant supplementation in pregnant women with low antioxidant status. J Obstet Gynaecol Res. 2012;38:1152‐1161. - PubMed
    1. Chen S, Li N, Mei Z, et al. Micronutrient supplementation during pregnancy and the risk of pregnancy‐induced hypertension: a randomized clinical trial. Clin Nutr. 2019;38:146‐151. - PMC - PubMed
    1. Gestational hypertension and preeclampsia: ACOG practice bulletin, Number 222. Obstet Gynecol. 2020;135:e237‐e260. - PubMed