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. 2022 May 24;11(11):2950.
doi: 10.3390/jcm11112950.

Pre-Interventional 3D-Printing-Assisted Planning of Flow Disrupter Implantation for the Treatment of an Intracranial Aneurysm

Guillaume Charbonnier  1   2   3 , Panagiotis Primikiris  1 , Benjamin Billottet  4 , Aurélien Louvrier  4   5 , Sergio Vancheri  1 , Serine Ferhat  1   2 , Alessandra Biondi  1   3
Affiliations

Pre-Interventional 3D-Printing-Assisted Planning of Flow Disrupter Implantation for the Treatment of an Intracranial Aneurysm

Guillaume Charbonnier et al. J Clin Med. .

Abstract

Intrasaccular flow disrupter devices (ISFD) have opened up new ways to treat intracranial aneurysms but choosing the correct size of ISFD can be challenging. We describe the first use of 3D printing to assist in the choice of ISFD, and we report an illustrative case. We developed a technique that uses preoperative angiography to make a plastic model of the aneurysm. We tested the deployment of different sizes of intrasaccular flow disruptor on the 3D model under fluoroscopy. The best devices were then used as the first-line strategy to treat the patient. The preoperative 3D printing helped in the successful selection of a first-line ISFD, which was not the one recommended by the manufacturer. Three-dimensional printing can provide interesting information regarding the treatment of intracranial aneurysms using ISFD. Further studies are needed to fully assess its benefits.

Keywords: 3D printing; aneurysm; contour; interventional neuroradiology; stroke; web.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 1
Figure 1
Injection of two 3D models (A,B) under fluoroscopy in the angio suite. Elongated point of entry of the vertebral artery (A) and internal carotid artery (B) (black arrowhead); elongated points of exit of the PICA and basilar trunk (A) middle cerebral artery (B) (white arrowheads) parallel to entry tube; soft waterproof plastic cylinders (black arrows).
Figure 2
Figure 2
The result of the 3D segmentation (A) and the 3D final print (B).
Figure 3
Figure 3
3D rotational angiography reconstruction of the left vertebral artery 3 months before the intervention.
Figure 4
Figure 4
(A) angiography image of WEB 6-3 without subtraction; (B) angiography image of WEB 6-3 with subtraction; (C) WEB 6-4 position 1; (D) Web 6-4 position 2; (E) CONTOUR 7; (F) CONTOUR 9.
Figure 5
Figure 5
(A) preoperative treatment angle; (B) subtracted postoperative image; (C) nonsubtracted postoperative image, showing the stagnation of the contrast agent in the dome of the aneurysm, suggesting successful occlusion (D) 3-month follow-up treatment angle (E) 3-month follow-up 3D angio-CT (F) 3-month follow-up fusion imaging.
See this image and copyright information in PMC

References

    1. Piotin M., Biondi A., Sourour N., Mounayer C., Jaworski M., Mangiafico S., Andersson T., Söderman M., Goffette P., Anxionnat R., et al. The LUNA Aneurysm Embolization System for Intracranial Aneurysm Treatment: Short-Term, Mid-Term and Long-Term Clinical and Angiographic Results. J. Neurointerv. Surg. 2018;10:e34. doi: 10.1136/neurintsurg-2018-013767. - DOI - PMC - PubMed
    1. Klisch J., Sychra V., Strasilla C., Liebig T., Fiorella D. The Woven EndoBridge Cerebral Aneurysm Embolization Device (WEB II): Initial Clinical Experience. Neuroradiology. 2011;53:599–607. doi: 10.1007/s00234-011-0891-x. - DOI - PubMed
    1. Bhogal P., Lylyk I., Chudyk J., Perez N., Bleise C., Lylyk P. The Contour-Early Human Experience of a Novel Aneurysm Occlusion Device. Clin. Neuroradiol. 2021;31:147–154. doi: 10.1007/s00062-020-00876-4. - DOI - PubMed
    1. Cagnazzo F., Marnat G., Ferreira I., Daube P., Derraz I., Dargazanli C., Lefevre P.-H., Gascou G., Riquelme C., Morganti R., et al. Comparison of Woven EndoBridge Device Sizing with Conventional Measurements and Virtual Simulation Using the Sim&Size Software: A Multicenter Experience. J. NeuroInterv. Surg. 2021;13:924–929. doi: 10.1136/neurintsurg-2020-017060. - DOI - PubMed
    1. Nagassa R.G., McMenamin P.G., Adams J.W., Quayle M.R., Rosenfeld J.V. Advanced 3D Printed Model of Middle Cerebral Artery Aneurysms for Neurosurgery Simulation. 3D Print. Med. 2019;5:11. doi: 10.1186/s41205-019-0048-9. - DOI - PMC - PubMed

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