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Review
. 2022 Jun 6;11(11):3226.
doi: 10.3390/jcm11113226.

Alternative Insertion Site of Nexplanon: Description of a Case Report and Systematic Review of the Literature

Guglielmo Stabile  1 , Carmelina Foti  2 , Denise Mordeglia  2 , Davide De Santo  1 , Francesco Paolo Mangino  1 , Antonio Simone Laganà  3 , Giuseppe Ricci  1   2
Affiliations
Review

Alternative Insertion Site of Nexplanon: Description of a Case Report and Systematic Review of the Literature

Guglielmo Stabile et al. J Clin Med. .

Abstract

The etonogestrel (ENG) implant is among the most effective reversible contraceptives. It can be a good option for patients with different chronic diseases due to no clinically significant effects on lipid metabolism or liver function. Some limitations in the use of this type of device are represented by social and psychiatric disorders, where the easy accessibility of the device becomes a negative feature. In these patients several cases of self-removal or damage to the device have been reported. We report the successful insertion of the Nexplanon® device into the scapular region in a young woman with a chronic psychiatric disorder. To verify the presence in the literature of other possible implantation sites, we performed a systematic review of the literature on Pubmed, Google scholar and Scopus from 2000 to 2021 using different combinations of the following terms: (Nexplanon), (contraceptive implant), (insertion). Two manuscripts with three cases were detected. Nexplanon® was implanted in the upper back. In all cases, there were no complications during the insertions and the follow up demonstrated no side effects with contraceptive efficacy. Our report and review is a further confirmation that the scapular region can become a valid insertion site, maintaining good efficacy and safety of the subcutaneous device.

Keywords: Nexplanon; alternative insertion; contraceptive implant; etonogestrel implant; implantation site; subcutaneous device.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Nexplanon’s insertion site.
Figure 2
Figure 2
PRISMA flow diagram.
See this image and copyright information in PMC

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