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Comment
. 2022 Aug 5;12(8):1833.
doi: 10.1158/2159-8290.CD-RW2022-103.

Engineered KRAS G12D-Reactive T Cells Show Promise in Pancreatic Cancer

No authors listed
Comment

Engineered KRAS G12D-Reactive T Cells Show Promise in Pancreatic Cancer

No authors listed. Cancer Discov. .

Abstract

T cells with engineered KRAS G12D-specific TCRs mediated regression of metastases in a patient with pancreatic cancer.

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Comment on

  • Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer.
    Leidner R, Sanjuan Silva N, Huang H, Sprott D, Zheng C, Shih YP, Leung A, Payne R, Sutcliffe K, Cramer J, Rosenberg SA, Fox BA, Urba WJ, Tran E. Leidner R, et al. N Engl J Med. 2022 Jun 2;386(22):2112-2119. doi: 10.1056/NEJMoa2119662. N Engl J Med. 2022. PMID: 35648703 Free PMC article.

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