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Case Reports
. 2022 Oct 1;38(10):e1613-e1619.
doi: 10.1097/PEC.0000000000002772. Epub 2022 Jun 8.

Comparison of Targeted and Routine Adolescent HIV Screening in a Pediatric Emergency Department

Affiliations
Case Reports

Comparison of Targeted and Routine Adolescent HIV Screening in a Pediatric Emergency Department

Colleen K Gutman et al. Pediatr Emerg Care. .

Abstract

Objectives: The aims of the study were (1) to compare targeted and routine HIV screening in a pediatric emergency department (PED) and (2) to compare provider documented HIV risk assessment with adolescent perception of HIV risk assessment conducted during the PED visit.

Methods: This prospective study ran concurrent to a PED routine HIV screening pilot. Adolescents could be tested for HIV by the PED provider per usual care (targeted testing); if not tested, they were approached for the routine screening pilot. A subset of adolescents completed a questionnaire on HIV risk. χ 2 analysis compared adolescents with targeted testing and routine screening. HIV-tested patients were asked if HIV risk was assessed; κ analysis compared this with documentation in the provider note.

Results: Over 4 months, 107 adolescents received targeted testing and 344 received routine screening. One 14-year-old patient tested positive by routine screening; this adolescent had 2 PED visits without targeted testing within 60 days. Compared with routine screening, adolescents with targeted testing were more likely female (82% vs 57%, P < 0.001), 16 years or older (71% vs 44%, P < 0.001), or had genitourinary/gynecologic concerns (48% vs 6%, P < 0.001). Adolescents with HIV risk factors were missed by targeted testing but received routine screening. Adolescents with documented HIV risk assessment were more likely to receive targeted testing. There was moderate agreement (κ = 0.61) between provider documentation and adolescent perception of HIV risk assessment.

Conclusions: There are gaps in PED HIV risk assessment and testing, which may miss opportunities to diagnose adolescent HIV. Routine HIV screening addresses these gaps and expands adolescent HIV testing in the PED.

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Conflict of interest statement

Disclosure: A.C.G. has received funding from Theratechnologies, Inc, for consulting. C.R.M. is the inventor or coinventor of several University of California, San Francisco-Benioff Children's Hospital Oakland patents/patent-pending applications that include nutritional supplements and biomarkers of cardiovascular disease, is an inventor of an Emory University School of Medicine patent application for a nutritional supplement, is a consultant for Pfizer, and has received research support from the US Food and Drug Administration and the National Institutes of Health. The other authors declare no conflict of interest.

Figures

FIGURE 1.
FIGURE 1.
Adolescent eligibility and participation in targeted HIV testing and the routine screening pilot. These adolescents could receive targeted testing at provider discretion but are not included in the sample or analyses. Exclusion criteria include: triage acuity level 1 (1), known HIV diagnosis (1), developmental delay and/or impairedmental status (70), and ineligible per provider (67). Reasons not approached include: discharged before able to be approached (123), repeat visits (68), and other (59). HIV testing of adolescents completing questionnaires: targeted testing (19), routine screening pilot (35), and declined testing (46).

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References

    1. Branson BM, Handsfield HH, Lampe MA, et al. Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep. 2006;55(Rr-14):1–17; quiz CE1–4. - PubMed
    1. INSIGHT START Study Group, Lundgren JD, Babiker AG, Gordin F, et al. Initiation of antiretroviral therapy in early asymptomatic HIV infection. N Engl J Med. 2015;373:795–807. - PMC - PubMed
    1. Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365:493–505. - PMC - PubMed
    1. Marks G, Crepaz N, Senterfitt JW, et al. Meta-analysis of high-risk sexual behavior in persons aware and unaware they are infected with HIV in the United States: implications for HIV prevention programs. J Acquir Immune Defic Syndr. 2005;39:446–453. - PubMed
    1. Haukoos JS, Hopkins E, Conroy AA, et al. Routine opt-out rapid HIV screening and detection of HIV infection in emergency department patients. JAMA. 2010;304:284–292. - PubMed

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