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Comment
. 2022 Jun 10;7(72):eabq1408.
doi: 10.1126/sciimmunol.abq1408. Epub 2022 Jun 10.

Three residues in the BTB domain promote a good partnership between NuRD and Thpok

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Three residues in the BTB domain promote a good partnership between NuRD and Thpok

Kazuki Okuyama et al. Sci Immunol. .

Abstract

Among the BTB-ZF transcription factor family, three amino acids in the BTB domain make Thpok unique in repressing cytotoxic lineage-related genes via recruitment of the NuRD chormatin-remodeling complex (see the related Research Article by Gao et al.).

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