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. 2022 Aug:166:113187.
doi: 10.1016/j.fct.2022.113187. Epub 2022 Jun 7.

Safety assessment of the insecticidal protein IPD079Ea from the fern, Ophioglossum pendulum

Anne B Carlson  1 , Carey A Mathesius  2 , Stephen Ballou  1 , Melissa N Fallers  3 , Tim A Gunderson  1 , Aideen Hession  1 , Henry Mirsky  1 , Brian Stolte  1 , John Zhang  1 , Rachel M Woods  1 , Rod A Herman  4 , Jason M Roper  3
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Free article

Safety assessment of the insecticidal protein IPD079Ea from the fern, Ophioglossum pendulum

Anne B Carlson et al. Food Chem Toxicol. 2022 Aug.
Free article

Abstract

As agricultural biotechnology continues to develop solutions for addressing crop pests through newly expressed proteins from novel source organisms, with different modes or sites of action and/or different spectra of activity, the safety of these proteins will be assessed. The results of hazard-identification and characterization studies for the insecticidal protein IPD079Ea, which is derived from a fern (Ophioglossum pendulum) and active against the maize pest western corn rootworm (Diabrotica virgifera virgifera, Coleoptera: Chrysomelidae) are provided. Collectively these results indicate that IPD079Ea is unlikely to present a hazard to human or animal health and support the safety of genetically modified maize expressing IPD079Ea.

Keywords: Biotechnology; IPD079Ea; Insecticide; Ophioglossum pendulum; PIP; Western corn rootworm.

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