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Case Reports
. 1987 May;32(5):554-7.
doi: 10.1007/BF01296041.

Carbamazepine-induced acute cholangitis

D Larrey, A Hadengue, D Pessayre, L Choudat, C DeGott, J P Benhamou
Case Reports

Carbamazepine-induced acute cholangitis

D Larrey et al. Dig Dis Sci. 1987 May.

Abstract

We report the case of a patient with carbamazepine-induced cholestasis in whom histologic examination showed acute cholangitis. This type of lesion broadens the spectrum of carbamazepine-induced liver injury which also includes granuloma and hepatocellular necrosis. Its association with marked hypereosinophilia suggests that carbamazepine may cause acute cholangitis through an immunoallergic mechanism.

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