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Meta-Analysis
. 2022 Jul;126(1):76-89.
doi: 10.1002/jso.26857.

Two- versus three-field lymphadenectomy for esophageal cancer. A systematic review and meta-analysis of early and late results

Letícia Nogueira Datrino  1 , Marina Feliciano Orlandini  1 , Maria Carolina Andrade Serafim  1 , Clara Lucato Dos Santos  1 , Victoria Andrade Modesto  1 , Guilherme Tavares  1 , Luca Schiliró Tristão  1 , Wanderley M Bernardo  1 , Francisco Tustumi  1   2   3
Affiliations
Meta-Analysis

Two- versus three-field lymphadenectomy for esophageal cancer. A systematic review and meta-analysis of early and late results

Letícia Nogueira Datrino et al. J Surg Oncol. 2022 Jul.

Abstract

This study aims to estimate whether prophylactic cervical lymphadenectomy for esophageal cancer influences the short- and long-term results through a systematic literature review and meta-analysis. Twenty-eight articles were selected in this systematic review, encompassing 9180 patients. Prophylactic neck lymphadenectomy for esophageal cancer should be performed with caution, as it is associated with worse short-term results compared to traditional two-field lymphadenectomy and does not improve long-term survival.

Keywords: esophageal cancer; esophagus; lymphadenectomy; meta-analysis; systematic review.

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References

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