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Review
. 2023 Jan 11;74(2):510-519.
doi: 10.1093/jxb/erac254.

The discovery of rubisco

Thomas D Sharkey  1
Affiliations
Review

The discovery of rubisco

Thomas D Sharkey. J Exp Bot. .

Abstract

Rubisco is possibly the most important enzyme on Earth, certainly in terms of amount. This review describes the initial reports of ribulose 1,5-bisphosphate carboxylating activity. Discoveries of core concepts are described, including its quaternary structure, the requirement for post-translational modification, and its role as an oxygenase as well as a carboxylase. Finally, the requirement for numerous chaperonins for assembly of rubisco in plants is described.

Keywords: 5-bisphosphate; Activase; Calvin–Benson cycle; chaperonin; history; photorespiration; ribulose 1; rubisco.

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