Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Jun 10;3(6):351-352.
doi: 10.1016/j.medj.2022.05.015.

Longitudinal sampling sheds light on SARS-CoV-2 fecal shedding dynamics

Affiliations
Comment

Longitudinal sampling sheds light on SARS-CoV-2 fecal shedding dynamics

Michael P Coryell et al. Med. .

Abstract

Persistent fecal shedding of SARS-CoV-2 viral RNA has remained a clinical feature of interest throughout the COVID-19 pandemic. In this issue of Med, Natarajan et al. report fecal shedding dynamics of individuals diagnosed with mild-to-moderate COVID-19 disease and sampled longitudinally for up to 10 months1.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests This article reflects the views of the authors and should not be construed to represent FDA’s views or policies. The authors declare no competing financial interests.

Comment on

References

    1. Natarajan A., Zlitni S., Brooks E.F., Vance S.E., Dahlen A., Hedlin H., Park R.M., Han A., Schmidtke D.T., Verma R., et al. Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection. Med. 2022;3:371–387. doi: 10.1016/j.medj.2022.04.001. - DOI - PMC - PubMed
    1. Wang W., Xu Y., Gao R., Lu R., Han K., Wu G., Tan W. Detection of SARS-CoV-2 in Different Types of clinical specimens. JAMA. 2020;323:1843–1844. doi: 10.1001/jama.2020.3786. - DOI - PMC - PubMed
    1. US Food and Drug Administration Information Pertaining to Additional Safety Protections Regarding Use of Fecal Microbiota for Transplantation - Screening Donors for COVID-19 and Exposure to SARS-CoV-2 and Testing for SARS-CoV-2. 2020. https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologi...
    1. Coryell M.P., Iakiviak M., Pereira N., Murugkar P.P., Rippe J., Williams D.B., Heald-Sargent T., Sanchez-Pinto L.N., Chavez J., Hastie J.L., et al. A method for detection of SARS-CoV-2 RNA in healthy human stool: a validation study. Lancet Microbe. 2021;2:e259–e266. doi: 10.1016/S2666-5247(21)00059-8. - DOI - PMC - PubMed
    1. Natarajan A., Han A., Zlitni S., Brooks E.F., Vance S.E., Wolfe M., Singh U., Jagannathan P., Pinsky B.A., Boehm A., Bhatt A.S. Standardized preservation, extraction and quantification techniques for detection of fecal SARS-CoV-2 RNA. Nat. Commun. 2021;12:5753. doi: 10.1038/s41467-021-25576-6. - DOI - PMC - PubMed

Publication types