Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 May 27:12:858242.
doi: 10.3389/fonc.2022.858242. eCollection 2022.

Lung Cancer Treatment: From Tradition to Innovation

Affiliations
Review

Lung Cancer Treatment: From Tradition to Innovation

Giuseppe Mangiameli et al. Front Oncol. .

Abstract

Lung cancer (LC) is the second most commonly diagnosed cancer and the primary cause of cancer death worldwide in 2020. LC treatment is associated with huge costs for patients and society; consequently, there is an increasing interest in the prevention, early detection with screening, and development of new treatments. Its surgical management accounts for at least 90% of the activity of thoracic surgery departments. Surgery is the treatment of choice for early-stage non-small cell LC. In this article, we discuss the state of the art of thoracic surgery for surgical management of LC. We start by describing the milestones of LC treatment, which are lobectomy and an adequate lymphadenectomy, and then we focus on the traditional and innovative minimally invasive surgical approaches available: video-assisted thoracoscopic surgery (VATS) and robotic-assisted thoracoscopic surgery (RATS). A brief overview of the innovation and future perspective in thoracic surgery will close this mini-review.

Keywords: RATS lobectomy; VATS lobectomy; lung cancer; open lobectomy; thoracic surgery.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. . Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin (2021) 71(3):209–49. doi: 10.3322/caac.21660 - DOI - PubMed
    1. Crucitti P, Gallo IF, Santoro G, Mangiameli G. Lung Cancer Screening With Low Dose CT: Experience at Campus Bio-Medico of Rome on 1500 Patients. Minerva Chir (2015) 70(6):393–9. - PubMed
    1. Mangiameli G, Longo F, Grasso RF, Iacopino A, Rocco R, Quintarelli F, et al. . Focus on Lung Cancer Screening Program at Campus Bio-Medico of Rome: Update on Over 3250 Patients. Minerva Chir (2017) 72(4):361–3. doi: 10.23736/S0026-4733.17.07336-9 - DOI - PubMed
    1. Infante M, Chiesa G, Solomon D, Morenghi E, Passera E, Lutman FR, et al. . Surgical Procedures in the DANTE Trial, A Randomized Study of Lung Cancer Early Detection With Spiral Computed Tomography: Comparative Analysis in the Screening and Control Arm. J Thorac Oncol (2011) 6(2):327–35. doi: 10.1097/JTO.0b013e318200f523 - DOI - PubMed
    1. Alloisio M, Infante M, Cariboni U, Testori A, Soto Parra H, Ravasi G. The Evolution of Surgery in non-Small Cell Lung Cancer. Tumori (2000) 86(5 Suppl 1):S42–6. doi: 10.1177/03008916000865s110 - DOI - PubMed

LinkOut - more resources