Patient with unresectable colorectal liver metastases and asymptomatic primary tumor: end of the debate!
- PMID: 35693410
- PMCID: PMC9186187
- DOI: 10.21037/hbsn-22-176
Patient with unresectable colorectal liver metastases and asymptomatic primary tumor: end of the debate!
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://hbsn.amegroups.com/article/view/10.21037/hbsn-22-176/coif). RA serves as an unpaid editorial board member of Hepatobiliary Surgery and Nutrition. The other author has no conflicts of interest to declare.
Comment on
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Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial.J Clin Oncol. 2021 Apr 1;39(10):1098-1107. doi: 10.1200/JCO.20.02447. Epub 2021 Feb 9. J Clin Oncol. 2021. PMID: 33560877 Free PMC article. Clinical Trial.
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Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment: The CAIRO4 Phase 3 Randomized Clinical Trial.JAMA Surg. 2021 Dec 1;156(12):1093-1101. doi: 10.1001/jamasurg.2021.4992. JAMA Surg. 2021. PMID: 34613339 Free PMC article. Clinical Trial.
References
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- Ferrand F, Malka D, Bourredjem A, et al. Impact of primary tumour resection on survival of patients with colorectal cancer and synchronous metastases treated by chemotherapy: results from the multicenter, randomised trial Fédération Francophone de Cancérologie Digestive 9601. Eur J Cancer 2013;49:90-7. 10.1016/j.ejca.2012.07.006 - DOI - PubMed
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- Ishihara S, Hayama T, Yamada H, et al. Prognostic impact of primary tumor resection and lymph node dissection in stage IV colorectal cancer with unresectable metastasis: a propensity score analysis in a multicenter retrospective study. Ann Surg Oncol 2014;21:2949-55. 10.1245/s10434-014-3719-1 - DOI - PubMed
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