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. 2020 Jun 4;3(3):240-243.
doi: 10.1093/pcmedi/pbaa021. eCollection 2020 Sep.

Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?

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Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?

Nikhat Khan et al. Precis Clin Med. .

Abstract

Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis (TB) in endemic regions including India, which has contributed the most to global TB burden. We argue here that a personalized medicine approach, to start with the N-acetyl transferase-2-isoniazid (NAT2-INH) model, could be a step forward in dealing with both these limitations in controlling TB in India.

Keywords: India; N-acetyl transferase-2; isoniazid; personalized medicine; tuberculosis.

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