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. 2022 Aug;36(8):e14750.
doi: 10.1111/ctr.14750. Epub 2022 Jun 28.

Sequential liver and kidney living donors: Making the ultimate gift twice

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Sequential liver and kidney living donors: Making the ultimate gift twice

Hasan Al Harakeh et al. Clin Transplant. 2022 Aug.

Abstract

There are nearly 150 living donors in the United States who donated more than one solid organ. Using our divisional database, we found 20 individuals who donated a liver and a kidney at different times. We performed a retrospective chart review of these donors, studying their motivating factors, complications and outcomes. The donors included 11 (55%) males and nine females. Thirteen (65%) donated the kidney before the liver. Fourteen (70%) were nondirected donors at the first donation, and four of the six directed donors in the first donation became nondirected in the second donation. Seventeen (85%) were nondirected at the second donation. Common reasons for donating the second time were a good experience with the first donation and knowing that one can donate again. Outcomes and the incidence of early complications were not significantly different after the 2nd versus the 1st donation. All donors recovered and currently are doing well. Our results show a significant number of dual organ donors are nondirected and motivated by their strong desire to help. A positive experience with the 1st donation often was the driving factor for the 2nd. A history of previous organ donation did not negatively impact the 2nd donation.

Keywords: donor evaluation; donor follow-up; donor hepatectomy; donor nephrectomy; donors and donation.

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REFERENCES

    1. Kirchner VA, Finger EB, Bellin MD, et al. Long-term outcomes for living pancreas donors in the modern era. Transplantation. 2016; 100(6): 1322-1328.
    1. Henderson ML, DiBrito SR, Thomas AG, et al. Landscape of living multiorgan donation in the United States: a registry-based cohort study. Transplantation. 2018; 102(7): 1148-1155.
    1. Fehrman-Ekholm I, Dunér F, Brink B, Tydén G, Elinder CG. No evidence of accelerated loss of kidney function in living kidney donors: results from a cross-sectional follow-up. Transplantation. 2001; 72(3): 444-449.
    1. Muzaale AD, Dagher NN, Montgomery RA, Taranto SE, McBride MA, Segev DL. Estimates of early death, acute liver failure, and long-term mortality among live liver donors. Gastroenterology. 2012; 142(2): 273-280.
    1. Abecassis MM, Fisher RA, Olthoff KM, et al. Complications of living donor hepatic lobectomy-a comprehensive report. Am J Transplant. 2012; 12(5): 1208-1217.

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