Prehospital low titer group O whole blood: Difficult to conclude?

Comment

Nicolas Cazes et al. J Trauma Acute Care Surg. 2022.

. 2022 Nov 1;93(5):e175.

doi: 10.1097/TA.0000000000003637. Epub 2022 Jun 14.

No abstract available

Comment in

Prehosptial low titer group O whole blood is feasible and safe: Results of a prospective randomized pilot trial.
Guyette FX, Sperry JL. Guyette FX, et al. J Trauma Acute Care Surg. 2022 Nov 1;93(5):e175-e176. doi: 10.1097/TA.0000000000003686. Epub 2022 Jun 14. J Trauma Acute Care Surg. 2022. PMID: 35696382 No abstract available.

Prehospital low titer group O whole blood is feasible and safe: Results of a prospective randomized pilot trial.
Guyette FX, Zenati M, Triulzi DJ, Yazer MH, Skroczky H, Early BJ, Adams PW, Brown JB, Alarcon L, Neal MD, Forsythe RM, Zuckerbraun BS, Peitzman AB, Billiar TR, Sperry JL. Guyette FX, et al. J Trauma Acute Care Surg. 2022 May 1;92(5):839-847. doi: 10.1097/TA.0000000000003551. Epub 2022 Jan 25. J Trauma Acute Care Surg. 2022. PMID: 35081595 Free PMC article. Clinical Trial.

1. Guyette FX, Zenati M, Triulzi DJ, Yazer MH, Skroczky H, Early BJ, et al. Prehosptial low titer group O whole blood is feasible and safe: results of a prospective randomized pilot trial [published online June 14, 2022]. J Trauma Acute Care Surg . doi:10.1097/TA.0000000000003686. - DOI
1. Shakur H, Roberts I, Bautista R, Caballero J, Coats T, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet . 2010;376(9734):23–32.
1. Spahn DR, Bouillon B, Cerny V, Duranteau J, Filipescu D, Hunt BJ, et al. The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition. Crit Care . 2019;23(1):98.
1. Guyette FX, Brown JB, Zenati MS, Early-Young BJ, Adams PW, Eastridge BJ, et al. Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury: a double-blind, placebo-controlled, randomized clinical trial. JAMA Surg . 2021;156(1):11–20.