Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1978 Jul;62(7):1085-7.

Chemoimmunotherapy for disseminated malignant melanoma: a prospective randomized study

W L Ramseur, F Richards 2nd, H B Muss, L Rhyne, M R Cooper, D R White, J J Stuart, C L Spurr
  • PMID: 356970
Clinical Trial

Chemoimmunotherapy for disseminated malignant melanoma: a prospective randomized study

W L Ramseur et al. Cancer Treat Rep. 1978 Jul.

Abstract

Twenty-eight patients with disseminated malignant melanoma were treated with DTIC (250 mg/m2 iv, Days 1--5) and actinomycin D (0.5 mg/day iv, Days 1--5) at 5-week intervals. Patients were randomly allocated to receive no immunotherapy or immunotherapy consisting of methanol extracted residue of bacillus Calmette-Guérin (0.5 mg intradermally; 100 microgram in five separate sites) every 5 weeks, concomitant with chemotherapy. Of these 28 evaluable patients, 13 received chemoimmunotherapy with one complete response (CR) and 15 received chemotherapy alone with one CR. Both responses occurred in lymph node metastases. No partial responses were seen.

PubMed Disclaimer

Publication types