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. 2022 Aug;19(8):499-500.
doi: 10.1038/s41569-022-00736-3.

Six lessons learned from the use of SGLT2 inhibitors in patients with heart failure

Milton Packer  1   2
Affiliations

Six lessons learned from the use of SGLT2 inhibitors in patients with heart failure

Milton Packer. Nat Rev Cardiol. 2022 Aug.
No abstract available

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References

    1. Giugliano, D. et al. SGLT-2 inhibitors and cardiorenal outcomes in patients with or without type 2 diabetes: a meta-analysis of 11 CVOTs. Cardiovasc. Diabetol. 20, 236 (2021). - DOI
    1. Packer, M. et al. Influence of neprilysin inhibition on the efficacy and safety of empagliflozin in patients with chronic heart failure and a reduced ejection fraction: the EMPEROR-Reduced trial. Eur. Heart J. 42, 671–680 (2021). - DOI
    1. Usman, M. S. et al. Robustness of outcomes in trials evaluating sodium-glucose co-transporter 2 inhibitors for heart failure. ESC Heart Fail. 9, 885–893 (2022). - DOI
    1. Packer, M. Does a target dose or a target heart rate matter to outcomes when prescribing β-blockers to patients with chronic heart failure? Circ. Cardiovasc. Qual. Outcomes 11, e004605 (2018). - DOI
    1. Packer, M. & McMurray, J. J. V. Rapid evidence-based sequencing of foundational drugs for heart failure and a reduced ejection fraction. Eur. J. Heart Fail. 23, 882–894 (2021). - DOI

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