PRC2 shields the potency of human stem cells

Sergi Aranda¹, Livia Condemi², Luciano Di Croce^{3

4}

Affiliations

¹ The Center for Genomic Regulation (CRG) and the Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. sergi.aranda@crg.eu.
² The Center for Genomic Regulation (CRG) and the Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
³ The Center for Genomic Regulation (CRG) and the Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. luciano.dicroce@crg.eu.
⁴ The Institució Catalana de Recerca i Estudis Avançats (ICREA) and the Universitat Pompeu Fabra (UPF), Barcelona, Spain. luciano.dicroce@crg.eu.

Comment

Sergi Aranda et al. Nat Cell Biol. 2022 Jun.

. 2022 Jun;24(6):806-808.

doi: 10.1038/s41556-022-00937-5.

Sergi Aranda¹, Livia Condemi², Luciano Di Croce^{3

4}

¹ The Center for Genomic Regulation (CRG) and the Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. sergi.aranda@crg.eu.
² The Center for Genomic Regulation (CRG) and the Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
³ The Center for Genomic Regulation (CRG) and the Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. luciano.dicroce@crg.eu.
⁴ The Institució Catalana de Recerca i Estudis Avançats (ICREA) and the Universitat Pompeu Fabra (UPF), Barcelona, Spain. luciano.dicroce@crg.eu.

No abstract available

Comment on

Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation.
Kumar B, Navarro C, Winblad N, Schell JP, Zhao C, Weltner J, Baqué-Vidal L, Salazar Mantero A, Petropoulos S, Lanner F, Elsässer SJ. Kumar B, et al. Nat Cell Biol. 2022 Jun;24(6):845-857. doi: 10.1038/s41556-022-00916-w. Epub 2022 May 30. Nat Cell Biol. 2022. PMID: 35637409 Free PMC article.
Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction.
Zijlmans DW, Talon I, Verhelst S, Bendall A, Van Nerum K, Javali A, Malcolm AA, van Knippenberg SSFA, Biggins L, To SK, Janiszewski A, Admiraal D, Knops R, Corthout N, Balaton BP, Georgolopoulos G, Panda A, Bhanu NV, Collier AJ, Fabian C, Allsop RN, Chappell J, Pham TXA, Oberhuemer M, Ertekin C, Vanheer L, Athanasouli P, Lluis F, Deforce D, Jansen JH, Garcia BA, Vermeulen M, Rivron N, Dhaenens M, Marks H, Rugg-Gunn PJ, Pasque V. Zijlmans DW, et al. Nat Cell Biol. 2022 Jun;24(6):858-871. doi: 10.1038/s41556-022-00932-w. Epub 2022 Jun 13. Nat Cell Biol. 2022. PMID: 35697783 Free PMC article.

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