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Review
. 2022 Jun 7:16:1731-1741.
doi: 10.2147/DDDT.S365292. eCollection 2022.

Research Progress of Liujunzi Decoction in the Treatment of Tumor-Associated Anorexia

Xipei Wu  1 , Yongzhao Dai  1 , Ke Nie  1
Affiliations
Review

Research Progress of Liujunzi Decoction in the Treatment of Tumor-Associated Anorexia

Xipei Wu et al. Drug Des Devel Ther. .

Abstract

Tumor-associated anorexia, mainly including cancerous anorexia and chemotherapy-induced anorexia, severely reduces the life quality of cancer patients but lacks of effective control until now. Liujunzi decoction (LJZD), a classical tonifying formula in traditional Chinese medicine, has promising effect in preventing and treating many kinds of anorexia. A growing number of evidence showed that LJZD is able to improve tumor-associated anorexia. Up to March 2022, a total of 58 articles studying LJZD or Rikkunshito (the name of LJZD in Japanese herbal medicine) in the treatment of tumor-associated anorexia are searched out in PubMed. This paper summarizes the effect of LJZD in ameliorating tumor-associated anorexia, in order to provide a theoretical basis for the clinical application of LJZD in treating tumor-associated anorexia, laying foundation for further research.

Keywords: Liujunzi decoction; review; tumor-associated anorexia.

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Conflict of interest statement

The authors declare that they have no conflicts of interest in this work.

Figures

Figure 1
Figure 1
The main pathological mechanisms of CA.
Figure 2
Figure 2
The main pathological mechanisms of CIA.
Figure 3
Figure 3
The main pathological mechanisms of LJZD in the treatment of CA and CIA.
See this image and copyright information in PMC

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