Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 May 13;14(5):e24968.
doi: 10.7759/cureus.24968. eCollection 2022 May.

Acute Unilateral Hypopyon Uveitis and Secondary Glaucoma in an Adult With Relapsing Acute Lymphoblastic Leukemia

Mithun Thulasidas  1 , Sagarika Patyal  2
Affiliations
Case Reports

Acute Unilateral Hypopyon Uveitis and Secondary Glaucoma in an Adult With Relapsing Acute Lymphoblastic Leukemia

Mithun Thulasidas et al. Cureus. .

Abstract

Anterior segment infiltration in acute lymphoblastic leukemia (ALL) presenting as hypopyon uveitis in an adult is rare. We report this case as an uncommon presentation in a patient in remission after chemotherapy for ALL. In addition to the hypopyon, the patient presented with congested eye caused by secondary raised intraocular pressure. There is a need to maintain a high index of clinical suspicion in uveitis cases, as early diagnosis of ocular malignancy can save vision. Atypical unilateral hypopyon, even in adults, can be an indication of relapsing ALL.

Keywords: acute lymphoblastic leukemia (all); hypopyon uveitis; leukemia; relapse; secondary glaucoma.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Anterior segment photograph showing (A) blood-streaked hypopyon and (B) nodular iris infiltrates (black arrow).
Figure 2
Figure 2. Anterior segment photograph showing a quiet eye with the resolution of hypopyon and iris infiltrates.
See this image and copyright information in PMC

References

    1. Ophthalmologic manifestations as the initial presentation of chronic myeloid leukemia: a review. Yassin MA, Ata F, Mohamed SF, et al. Surv Ophthalmol. 2022;67:530–543. - PubMed
    1. Ophthalmic manifestations of leukemia. Schachat AP, Markowitz JA, Guyer DR, Burke PJ, Karp JE, Graham ML. Arch Ophthalmol. 1989;107:697–700. - PubMed
    1. Relapsing acute myeloid leukemia manifesting as hypopyon uveitis. Ayliffe W, Foster CS, Marcoux P, Upton M, Finkelstein M, Kuperwaser M, Legmann A. Am J Ophthalmol. 1995;119:361–364. - PubMed
    1. Uveitis masquerade syndromes. Rothova A, Ooijman F, Kerkhoff F, Van Der Lelij A, Lokhorst HM. Ophthalmology. 2001;108:386–399. - PubMed
    1. Variations in the presentation of primary intraocular lymphoma: case reports and a review. Gill MK, Jampol LM. Surv Ophthalmol. 2001;45:463–471. - PubMed

Publication types