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. 1987 Mar;23(3):568-70.

[Analysis of hypotheses and simulation of selection for a suppressor affecting the manifestations of the fused gene in mice]

[Article in Russian]
  • PMID: 3569900

[Analysis of hypotheses and simulation of selection for a suppressor affecting the manifestations of the fused gene in mice]

[Article in Russian]
I N Shindialov et al. Genetika. 1987 Mar.

Abstract

The t12 haplotype decreases sharply manifestation of fused gene in mice. The selection for increasing the penetrance of fused gene was made in Fu/t12 stock. The different computer models of selection process were compared. The hypothesis giving the best coincidence with experimental data supposes the presence of a semidominant gene suppressing the effect of t12 on Fu gene in chromosome 8.

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