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Comparative Study
. 2022 Aug;23(8):e13668.
doi: 10.1002/acm2.13668. Epub 2022 Jun 15.

Comparison of Eclipse Smart Segmentation and MIM Atlas Segment for liver delineation for yttrium-90 selective internal radiation therapy

Jun Li  1 , Rani Anne  1
Affiliations
Comparative Study

Comparison of Eclipse Smart Segmentation and MIM Atlas Segment for liver delineation for yttrium-90 selective internal radiation therapy

Jun Li et al. J Appl Clin Med Phys. 2022 Aug.

Abstract

Purpose: The aim was to compare Smart Segmentation of Eclipse treatment planning system and Atlas Segment of MIM software for liver delineation for resin yttrium-90 (Y-90) procedures.

Materials and methods: CT images of 20 patients treated with resin Y-90 selective internal radiation therapy (SIRT) were tested. Liver contours generated with Smart Segmentation and Atlas Segment were compared with physician manually delineated contours. Dice similarity coefficient (DSC), mean distance to agreement (MDA), and ratio of volume (RV) were calculated. The contours were evaluated with activity calculations and ratio of activity (RA) was calculated.

Results: Mean DSCs were 0.77 and 0.83, MDAs were 0.88 and 0.71 cm, mean RVs were 0.95 and 1.02, and mean RAs were 1.00 and 1.00, for Eclipse and MIM results, respectively.

Conclusion: MIM outperformed Eclipse in both DSC and MDA, whereas the differences in liver volumes and calculated activities were statistically insignificant between the Eclipse and MIM results. Both auto-segmentation tools can be used to generate initial liver contours for resin Y-90 SIRT, which need to be reviewed and edited by physicians.

Keywords: Eclipse; MIM; auto-segmentation; liver delineation; resin yttrium-90.

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Conflict of interest statement

The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

Figures

FIGURE 1
FIGURE 1
Liver contours generated by manual delineation (red), Eclipse Smart Segmentation (blue), and MIM Atlas Segment (yellow), shown in axial (left), sagittal (middle), and coronal (right) views
FIGURE 2
FIGURE 2
Box plot of Dice similarity coefficient (DSC) between the automatically segmented (Eclipse, MIM) and manually delineated liver contours
FIGURE 3
FIGURE 3
Box plot of mean distance to agreement (MDA) between the automatically segmented (Eclipse, MIM) and manually delineated liver contours
FIGURE 4
FIGURE 4
Box plot of ratio of volume (RV): ratio of the automatically segmented (Eclipse, MIM) to the manually delineated liver volume
FIGURE 5
FIGURE 5
Box plot of ratio of activity (RA): ratio of the activity calculated using the automatically segmented (Eclipse, MIM) to the activity calculated using manually delineated liver volume
See this image and copyright information in PMC

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