Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun 1;5(6):e2217234.
doi: 10.1001/jamanetworkopen.2022.17234.

Accuracy of Rapid Antigen vs Reverse Transcriptase-Polymerase Chain Reaction Testing for SARS-CoV-2 Infection in College Athletes During Prevalence of the Omicron Variant

Affiliations

Accuracy of Rapid Antigen vs Reverse Transcriptase-Polymerase Chain Reaction Testing for SARS-CoV-2 Infection in College Athletes During Prevalence of the Omicron Variant

Jessica Tsao et al. JAMA Netw Open. .

Abstract

This case series evaluates the performance of rapid antigen tests in detecting SARS-CoV-2 infection in college athletes during prevalence of a dominant Omicron variant.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: Dr Kussman reported receiving personal fees from Fresno Madera Medical Society outside the submitted work. Dr Abrams reported owning stock or stock options from AxGen and Cytonics; serving as a board or committee member for the American Academy of Orthopaedic Surgeons, American Orthopaedic Society for Sports Medicine, and International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine; receiving cadaver labs and equipment for educational purposes from Arthrex and Stryker; receiving consulting fees from Bioventus Inc, Cytonics, Fidia Pharma, and RubiconMD; and serving as an unpaid consultant for TeachAids. No other disclosures were reported.

Figures

Figure.
Figure.. SARS-CoV-2 Reverse Transcriptase–Polymerase Chain Reaction Cycle Threshold Values by Rapid Antigen Test (RAT) Results and COVID-19 Symptoms
Data are from 723 student athletes undergoing testing for SARS-CoV-2. Solid lines indicate median cycle threshold value; dotted lines, cycle threshold value quartiles.

References

    1. Schrom J, Marquez C, Pilarowski G, et al. Comparison of SARS-CoV-2 reverse transcriptase polymerase chain reaction and BinaxNOW rapid antigen tests at a community site during an Omicron surge: a cross-sectional study. Ann Intern Med. Published online March 15, 2022. doi: 10.7326/M22-0202 - DOI - PMC - PubMed
    1. Adamson B, Sikka R, Wyllie AL, Premsrirut P. Discordant SARS-CoV-2 PCR and rapid antigen test results when infectious: a December 2021 occupational case series. medRxiv. Preprint published online January 5, 2022. doi: 10.1101/2022.01.04.22268770 - DOI
    1. Regan J, Flynn JP, Choudhary MC, et al. Detection of the Omicron variant virus with the Abbott BinaxNow SARS-CoV-2 rapid antigen assay. Open Forum Infect Dis. 2022;9(3):ofac022. doi: 10.1093/ofid/ofac022 - DOI - PMC - PubMed
    1. Deerain J, Druce J, Tran T, et al. Assessment of the analytical sensitivity of 10 lateral flow devices against the SARS-CoV-2 Omicron variant. J Clin Microbiol. 2022;60(2):e0247921. doi: 10.1128/jcm.02479-21 - DOI - PMC - PubMed
    1. Khandker SS, Nik Hashim NHH, Deris ZZ, Shueb RH, Islam MA. Diagnostic accuracy of rapid antigen test kits for detecting SARS-CoV-2: a systematic review and meta-analysis of 17,171 suspected COVID-19 patients. J Clin Med. 2021;10(16):3493. doi: 10.3390/jcm10163493 - DOI - PMC - PubMed

Substances

Supplementary concepts