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. 2022 Sep;50(7):803-805.
doi: 10.1111/ceo.14125. Epub 2022 Jun 30.

Survey of intravitreal injection outcomes amongst ophthalmologists using pre-filled aflibercept syringes

Daniel J Lee  1 , Brittni A Scruggs  1 , Ambar Faridi  1   2 , Erik Sánchez  3 , Merina Thomas  1
Affiliations

Survey of intravitreal injection outcomes amongst ophthalmologists using pre-filled aflibercept syringes

Daniel J Lee et al. Clin Exp Ophthalmol. 2022 Sep.
No abstract available

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Conflict of interest statement

Conflict of interest: None

Figures

Figure 1:
Figure 1:
Perceived differences with aflibercept PFS when compared to other medications/preparations. (A) Nearly one third of respondents (31%) perceived an increased frequency in IOP spikes immediately following aflibercept PFS use when compared to other medications/preparations. (B) Most respondents (49/72, 68%) believed that more force was needed with aflibercept PFS when compared to vial-prepared injections.
Figure 2:
Figure 2:
Reporting of significant vision loss following intravitreal aflibercept injection. Almost twice as many ophthalmologists reported at least 1 episode of significant vision loss with aflibercept PFS use (51/76, 67%) when compared to the vial preparation (27/76, 35%).
See this image and copyright information in PMC

References

    1. Sassalos TM, Paulus YM. Prefilled syringes for intravitreal drug delivery. Clin Ophthalmol 2019; 13: 701–6. - PMC - PubMed
    1. Lee DJ, Scruggs BA, Sánchez E, Thomas M, Faridi A. Transient vision loss associated with pre-filled aflibercept syringes: a case series and analysis of injection force. Ophthalmol Sci 2022. - PMC - PubMed
    1. Gallagher K, Raghuram AR, Williams GS, Davies N. Pre-filled aflibercept syringes-variability in expressed fluid volumes and a case series of transient central retinal artery occlusions. Eye (Lond) 2020. - PMC - PubMed