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Comparative Study
. 2022 Jul 19;328(3):296-298.
doi: 10.1001/jama.2022.9609.

Association of Omicron vs Wild-type SARS-CoV-2 Variants With Hospital-Onset SARS-CoV-2 Infections in a US Regional Hospital System

Michael Klompas  1 , Michael C Pandolfi  2 , Ansa B Nisar  2 , Meghan A Baker  1 , Chanu Rhee  1
Affiliations
Comparative Study

Association of Omicron vs Wild-type SARS-CoV-2 Variants With Hospital-Onset SARS-CoV-2 Infections in a US Regional Hospital System

Michael Klompas et al. JAMA. .

Abstract

This retrospective hospital-based study examines all SARS-CoV-2 nosocomial infections in 1 US health care system during the Omicron surge vs an earlier wave when wild-type variants predominated.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Klompas reported receiving grants from the Centers for Disease Control and Prevention (CDC) and the Agency for Healthcare Research and Quality, and royalties from UpToDate outside the submitted work. Dr Baker reported receiving grants from CDC during the conduct of the study. Dr Rhee reported receiving royalties from UpToDate and consulting fees from Cytovance and Pfizer outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Incidence of Hospital-Onset Infection
Months reflect the date of diagnosis. C, Direct care personnel included physicians, nurses, nursing support personnel, physician assistants, physical therapists, occupational therapists, speech therapists, and respiratory therapists.
See this image and copyright information in PMC

References

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    1. Klompas M, Baker MA, Rhee C, et al. A SARS-CoV-2 cluster in an acute care hospital. Ann Intern Med. 2021;174(6):794-802. doi: 10.7326/M20-7567 - DOI - PMC - PubMed
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    1. Klompas M, Karan A. Preventing SARS-CoV-2 transmission in health care settings in the context of the Omicron variant. JAMA. 2022;327(7):619-620. doi: 10.1001/jama.2022.0262 - DOI - PubMed

Publication types

Supplementary concepts