Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov;16(11):E575-E578.
doi: 10.5489/cuaj.7915.

Case - Salvage nerve-sparing radical cystectomy for pediatric rhabdomyosarcoma of the bladder

Jakob Klemm  1 , Michael Rink  1 , Silke Riechardt  1 , Carolin Stiel  1 , Franziska Büscheck  2 , Guido Sauter  2 , Roland Dahlem  1 , Margit Fisch  1 , Malte W Vetterlein  1
Affiliations

Case - Salvage nerve-sparing radical cystectomy for pediatric rhabdomyosarcoma of the bladder

Jakob Klemm et al. Can Urol Assoc J. 2022 Nov.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: The authors do not report any competing personal or financial interests related to this work.

Figures

Figure 1
Figure 1
Initial abdominal ultrasound showing a cauliflower-like, hyperechoic tumor with approximately 3.0 cm in diameter and presumed infiltration of the bladder wall and the urethra in the (A) transverse and (B) sagittal scan plane.
Figure 2
Figure 2
Magnetic resonance imaging of the abdomen after completion of chemotherapy and proton therapy showing residual disease with a thickened bladder outlet and residual irregularities in the proximal urethra in the (A) sagittal and (B) coronal plane.
Figure 3
Figure 3
Hematoxylin and eosin stains of the cystectomy specimen showing polytope residual infiltrates of a botryoid embryonal rhabdomyosarcoma. Bars represent (A) 200 μm and (B) 50 μm, respectively. (A) A regular urothelium on the surface overlying a malignant neoplasm, which is arranged in form of a cambium layer (subepithelial condensation of the tumor), the classic feature of a botryoid rhabdomyosarcoma. The higher magnification (B) shows polymorphic tumor cells (rhabdomyoblasts) in the lamina propria with broad eosinophilic cytoplasm and pleomorphic nuclei.
See this image and copyright information in PMC

References

    1. Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2022. CA Cancer J Clin. 2022;72:7–33. doi: 10.3322/caac.21708. - DOI - PubMed
    1. Rudzinski ER, Anderson JR, Hawkins DS, et al. The World Health Organization classification of skeletal muscle tumors in pediatric rhabdomyosarcoma: A report from the Children’s Oncology Group. Arch Pathol Lab Med. 2015;139:1281–7. doi: 10.5858/arpa.2014-0475-OA. - DOI - PMC - PubMed
    1. Schlegel PN, Walsh PC. Neuroanatomical approach to radical cystoprostatectomy with preservation of sexual function. J Urol. 1987;138:1402–6. doi: 10.1016/S0022-5347(17)43655-X. - DOI - PubMed
    1. Gilbert SM, Dunn RL, Hollenbeck BK, et al. Development and validation of the Bladder Cancer Index: A comprehensive, disease specific measure of health-related quality of life in patients with localized bladder cancer. J Urol. 2010;183:1764–9. doi: 10.1016/j.juro.2010.01.013. - DOI - PubMed
    1. Saltzman AF, Cost NG. Current treatment of pediatric bladder and prostate rhabdomyosarcoma. Curr Urol Rep. 2018;19:11. doi: 10.1007/s11934-018-0761-8. - DOI - PubMed

LinkOut - more resources