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. 2022 Jun 15;22(1):170.
doi: 10.1186/s12874-022-01648-z.

Investigating factors associated with the number of rehospitalizations among patients with schizophrenia disorder using penalized count regression models

Mahya Arayeshgari  1 , Ghodratollah Roshanaei  1   2 , Ali Ghaleiha  3   4 , Jalal Poorolajal  2   5 , Leili Tapak  6   7
Affiliations

Investigating factors associated with the number of rehospitalizations among patients with schizophrenia disorder using penalized count regression models

Mahya Arayeshgari et al. BMC Med Res Methodol. .

Abstract

Background: Schizophrenia is a chronic, severe, and debilitating mental disorder always considered one of the recurrent psychiatric diseases. This study aimed to use penalized count regression models to determine factors associated with the number of rehospitalizations of schizophrenia disorder.

Methods: This retrospective cohort study was performed on 413 schizophrenic patients who had been referred to the Sina (Farshchian) Educational and Medical Center in Hamadan, Iran, between March 2011 and March 2019. The penalized count regression models were fitted using R.3.5.2.

Results: About 73% of the patients were male. The mean (SD) of age and the number of rehospitalizations were 36.16 (11.18) years and 1.21 (2.18), respectively. According to the results, longer duration of illness (P < 0.001), having a positive family history of psychiatric illness (P = 0.017), having at least three children (P = 0.013), unemployment, disability, and retirement (P = 0.025), residence in other Hamadan province townships (P = 0.003) and having a history of arrest/prison (P = 0.022) were significantly associated with an increase in the number of rehospitalizations.

Conclusion: To reduce the number of rehospitalizations among schizophrenic patients, it is recommended to provide special medical services for patients who do not have access to specialized medical centers and to create the necessary infrastructure for the employment of patients.

Keywords: Count Regression Model; Minimum Concave Penalty; Random Forest; Rehospitalization; Schizophrenia; Variable Selection.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Bar plot of the number of rehospitalizations of schizophrenic patients
Fig. 2
Fig. 2
Hierarchy chart of fitted models
See this image and copyright information in PMC

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References

    1. World Health Organization. Schizophrenia 2019. Available from: https://www.who.int/news-room/fact-sheets/detail/schizophrenia.
    1. Vigo D, Thornicroft G, Atun R. Estimating the true global burden of mental illness. Lancet Psychiatry. 2016;3(2):171–178. doi: 10.1016/S2215-0366(15)00505-2. - DOI - PubMed
    1. James SL, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 2018;392(10159):1789–1858. doi: 10.1016/S0140-6736(18)32279-7. - DOI - PMC - PubMed
    1. Mohammadi MR, Davidian H, Nourbala AA, Malek Afzali H, Naghavi HR, Pouretemad HR, et al. An epidemiological study of psychiatric disorders in iran, 2001. Hakim Res J. 2003;6(1):55–67. - PubMed
    1. WHO & Ministry of Health and Medical education. WHO-AIMS report on mental health system in the Islamic Republic of Iran. Tehran, the Islamic Republic of Iran; 2006.

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