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Review
. 2022 Feb 25;9(2):76-81.
doi: 10.1055/s-0042-1743572. eCollection 2022 Jun.

The Human Genetics of Dental Anomalies

Mahamad Irfanulla Khan  1 , Nadeem Ahmed  2 , Praveen Kumar Neela  3 , Nayeem Unnisa  4
Affiliations
Review

The Human Genetics of Dental Anomalies

Mahamad Irfanulla Khan et al. Glob Med Genet. .

Abstract

The development of tooth is a highly complex procedure and mastered by specific genetic programs. Genetic alterations, environmental factors, and developmental timing can disturb the execution of these programs, and result in various dental anomalies like hypodontia/oligodontia, and supernumerary teeth, which are commonly seen in our clinical practice. Advances in molecular research enabled the identification of various genes involved in the pathogenesis of dental anomalies. In the near future, it will help provide a more accurate diagnosis and biological-based treatment for these anomalies. In this article, we present the molecular phenomenon of tooth development and the genetics of various dental anomalies.

Keywords: dental anomalies; genes; genetics; mutations; tooth development.

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Conflict of interest statement

Conflict of Interest None declared.

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