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Comment
. 2022 Jun 15;110(12):1889-1890.
doi: 10.1016/j.neuron.2022.05.023.

Fatherhood is life changing: Uncovering structural and functional changes in the dad brain

Richard G Dickson  1 , Matthew W Jacobs  1 , Euiseok J Kim  2
Affiliations
Comment

Fatherhood is life changing: Uncovering structural and functional changes in the dad brain

Richard G Dickson et al. Neuron. .

Abstract

What are the cellular-level structural and functional changes underlying newly adaptive behaviors in the mammalian brain? In this issue of Neuron, Inada et al. (2022) identify the brain-wide connectivity and synaptic plasticity changes of hypothalamic oxytocin+ neurons in male mice contributing to their parental behaviors.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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References

    1. Grinevich V, and Stoop R (2018). Interplay between oxytocin and sensory systems in the orchestration of socio-emotional behaviors. Neuron 99, 887–904. 10.1016/j.neuron.2018.07.016. - DOI - PubMed
    1. Inada K, Hagihara M, Tsujimoto K, Abe T, Konno A, Hirai H, Kiyonari H, and Miyamichi K (2022). Plasticity of neural connections underlying oxytocin-mediated parental behaviors of male mice. Neuron 110, 2009–2023. 10.1016/j.neuron.2022.03.033. - DOI - PubMed
    1. Knobloch HS, Charlet A, Hoffmann LC, Eliava M, Khrulev S, Cetin AH, Osten P, Schwarz MK, Seeburg PH, Stoop R, and Grinevich V (2012). Evoked axonal oxytocin release in the central amygdala attenuates fear response. Neuron 73, 553–566. 10.1016/j.neuron.2011.11.030. - DOI - PubMed
    1. Liu M, Kim DW, Zeng H, and Anderson DJ (2022). Make war not love: The neural substrate underlying a state-dependent switch in female social behavior. Neuron 110, 841–856.e6. 10.1016/j.neuron.2021.12.002. - DOI - PMC - PubMed
    1. Owen SF, Tuncdemir SN, Bader PL, Tirko NN, Fishell G, and Tsien RW (2013). Oxytocin enhances hippocampal spike transmission by modulating fast-spiking interneurons. Nature 500, 458–462. 10.1038/nature12330. - DOI - PMC - PubMed

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