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Case Reports
. 2022 Dec;51(12):2341-2346.
doi: 10.1007/s00256-022-04088-4. Epub 2022 Jun 16.

A report of an intracortical chondroblastoma of the diaphysis in a skeletally mature patient

Madeline A Sauer  1 , Paul Stegelmeier  1 , Julia R Crim  2 , Lester J Layfield  3 , Andrea Evenski  4
Affiliations
Case Reports

A report of an intracortical chondroblastoma of the diaphysis in a skeletally mature patient

Madeline A Sauer et al. Skeletal Radiol. 2022 Dec.

Abstract

Chondroblastomas characteristically occur in skeletally immature patients, and arise within the medullary canal of the epiphysis. We report a rare case of an intracortical chondroblastoma arising in the diaphysis, and occurring in an adult in his 3rd decade of life. Immunohistochemistry results were critical to confirmation of this rare diagnosis, with immunohistochemistry showing S100, DOG1, and H3K36me3 positivity in the neoplastic cells.

Keywords: Chondroblastoma; Diaphyseal bone neoplasm; H3K36 mutation; Intracortical bone neoplasm.

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