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. 2022 Jun;27(24):2200448.
doi: 10.2807/1560-7917.ES.2022.27.24.2200448.

Estimated incubation period for monkeypox cases confirmed in the Netherlands, May 2022

Fuminari Miura  1   2 , Catharina E van Ewijk  1   3 , Jantien A Backer  1 , Maria Xiridou  1 , Eelco Franz  1 , Eline Op de Coul  1 , Diederik Brandwagt  1 , Brigitte van Cleef  1 , Gini van Rijckevorsel  1   4 , Corien Swaan  1 , Susan van den Hof  1 , Jacco Wallinga  1   5
Affiliations

Estimated incubation period for monkeypox cases confirmed in the Netherlands, May 2022

Fuminari Miura et al. Euro Surveill. 2022 Jun.

Abstract

In May 2022, monkeypox outbreaks have been reported in countries not endemic for monkeypox. We estimated the monkeypox incubation period, using reported exposure and symptom-onset times for 18 cases detected and confirmed in the Netherlands up to 31 May 2022. Mean incubation period was 9.0 [corrected] days (5th-95th percentiles: 4.2-17.3), underpinning the current recommendation to monitor or isolate/quarantine case contacts for 21 days. However, as the incubation period may differ between different transmission routes, further epidemiological investigations are needed.

Keywords: Monkeypox; epidemiology; incubation period; modelling; poxvirus; quarantine; smallpox; statistics; symptom onset; varicella virus infection (chickenpox).

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure
Figure
Estimated cumulative density functions, according to different parametric distributions and empirical cumulative density function of incubation periods reported for monkeypox cases in the Netherlands, May 2022 (n = 18 cases)
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