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. 2022 Sep 29;11(9):404-407.
doi: 10.1093/jpids/piac044.

Incidence of Intussusception in Bamako, Mali, Before and After the Introduction of Rotavirus Vaccine

Anna Roose  1 , Adama Mamby Keita  2 , Milagritos D Tapia  1   3 , Samba O Sow  2 , T Christopher Mast  4 , Karen L Kotloff  1   3
Affiliations

Incidence of Intussusception in Bamako, Mali, Before and After the Introduction of Rotavirus Vaccine

Anna Roose et al. J Pediatric Infect Dis Soc. .

Abstract

Pentavalent rotavirus vaccine has been associated with a small increase in intussusception, but pre- and post-introduction data are lacking in many low-resource settings. Using chart review and prospective surveillance data, intussusception incidence was estimated in Bamako, Mali. The mean annual intussusception incidence post-introduction was not significantly different from that of pre-introduction.

Keywords: Mali; RotaTeq; immunization; intussusceptions; post-marketing surveillance.

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Figures

Figure 1.
Figure 1.
Incidence and counts of intussusception cases among Bamako infants, before and after RV5 introduction. Lines estimate incidence under alternative population growth models. The lower dashed line estimates incidence under the assumption that the population would grow twice as quickly as estimated, and the upper dotted line represents a population that has remained static since 2009. Bars estimate the number of intussusception cases identified annually.
See this image and copyright information in PMC

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